2025 NCAA Tournament Upsets: Expert Bracket Picks & Predictions

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Can you truly predict March Madness? No, you can't, and that's precisely why the 2025 NCAA Men's Basketball Tournament upsets will be so captivating! Every year, brackets are busted, dreams are shattered, and Cinderella stories emerge from seemingly nowhere. The beauty of the tournament lies in its unpredictability, and 2025 promises to be no different.

The tournament technically commenced with the First Four games on Monday night, serving as a prelude to the main event. But the real action unfolds on Thursday, when a staggering 16 teams will face elimination, making way for the Sweet Sixteen. While expert predictions for the Midwest and South brackets are abundant, the true essence of March Madness lies in the inevitable upsets that defy all expectations. As college basketball obsessives, we're already deep into dissecting potential matchups and agonizing over bubble teams, all while holding onto the hope of witnessing a Cinderella run. Predicting the NCAA Men's Basketball Tournament bracket in 2025 is a blend of art, science, and a hefty dose of educated guesswork.